Daria is coming out on DVD Spring of 2010!
This has been in the works since last summer, but there is now an official teaser trailer by MTV.

The current plan is to release Daria as a “reasonably priced” complete series set, which will include all five seasons of the show and both television movies (Is It Fall Yet? and Is It College Yet?). The studio also seems committed to including as many worthwhile extras as possible, such as Daria talk show appearances, Sarcastathons, informative specials and perhaps the unaired pilot! (via)